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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23e87d962e44edc4b5c402830a91dd281a463d48df4c0e7787fc9cb6ae77e9df' 
  AND token = 'ZfG22753p8SO1Ka/zHcdqcmCyCcfUS7ZfL1Mr2WdDBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}