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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c68e4c6c05914c2e98c4e7978c53867b90b753418191bf5da7e99990dac6185' 
  AND token = '1UutAHmG4jcSO21az0tOshWl1/BZEz7Urm2rNVCRFOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}