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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561f6a18d704ae8750816ebb2fac4d67f0862bb560b5a6209ee6c3c8a77b4183' 
  AND token = 'GX9XG/xu+oyF0htthe0c/8qzkeFdcK8fQdXSGfWxL8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}