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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f4f0089f0ec232f7c4ef48fa36f5d2da21394120a781bf7093795a8c393b04' 
  AND token = '5nP4ZCbXeS7godsK9Ar+DcbHIzN6mvfXbjBZzxpzuAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}