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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '220905cc50c7ba06b6bc60bd1caf9b8d6506b2b25a601405bb02a8feabecb6dc' 
  AND token = '05W3oca43z8ag/vAH7/6WJuE2vfGIAi/+yoIgAI69UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}