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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f5673446136e854898e5131aa251a4488c65decdd23b3d6a3d54192a7b5e8ff' 
  AND token = '6yT+WBKiPeudvUmq/aV15I+Kemm2Ufp+nC9jtiy0mb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}