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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea216f6e5a6b0e4f95c1b9badc15e84764150e8de30d70e16397fefd60734c99' 
  AND token = 'fuG5OmlyhsNu1YH/EFNdlyw2BHQ2WkAXe6GKI1gNYqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}