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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379f6f922ecff16fa20d367d1cadaae660c98fc9698298f50aa2d7c69070c4ab' 
  AND token = 'P/7uDHXQc9zrKXeAbhiZ8+ynkVdxwJwSHDWyf8Ip94M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}