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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a9442ca83ff9a0149fa5ae3dac62aecb42b882358abd11d5a08a043ab122959' 
  AND token = 'yDOUfwlOtiUUKhAqqx//c1mTTj85RPs2toA3ie1xjJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}