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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f77e8debfc21bf2e49901f80fcf5f5aa8b7d51e80c644b3adb23b91c599481c' 
  AND token = 'U1HnY1ae2RrJEk2J175zEZfLAcDbMfM+MULEcyPvfdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}