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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1240ab7d86808dd2bc3dd19835b6a6a78764a6a5b3226d27efe59a52b99da1b' 
  AND token = 'VRB2mhCw7fuLRaAP5t7aotXh3nhCgiZm07Hj6zhEk70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}