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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd81d28df48b7a797d18c45fe9ba8f191303f90a9130579df11b301508f7108cb' 
  AND token = 'v6IcAlTGqtJ5n69Gz57gE3fQUAEaMIy3ITi9p/0BDLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}