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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75e64a43dec65ba1c8d1db11f83948ae989a2ea074003db0f5209afd2dbae428' 
  AND token = 'RYRpPyGAKxVNbAdoyqZoXEPEYnCQfNWcpTkypkB1wZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}