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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aec4bb11d044e4e5f3adb168a7b65c46d051625414d72dfdb66f87da17ad775a' 
  AND token = 'f2KVT2/mOP7V5k1UTHCgwo8jrm/oV8X6Db31iisixx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}