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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a53d1859cb3db1c92714dc57aa7693939400c33db3c52511471c0254ace846' 
  AND token = 'Wy0l5xNZcr544UtM3g1hy7GuJHRTw+RC5a7txUYmHuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}