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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5641d39ce6a00f1480dd66ead04054dfc132cd384b110f5fa0b1f46f0ceb9447' 
  AND token = '0T/6I4j3FKP36J7FY1qwD6NrBltuQHi2SzbJhBD5uCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}