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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9ea8f466f91c1f390912cc78fab68c118ea2d018397c6a4273d1ad12fe7d2a3' 
  AND token = 'yVTk/Gtzz2Va0cjxfIL/03nd4qsO4QUIXkQHN9n+jeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}