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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cce70c4cfbb89cca6555a1f9492afd381635490dccac0a2dfc9b4f8c17c2912' 
  AND token = '574FESkLZB2yFeUcnxnsxKRtANQfAUtIZ3YEWB5kyLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}