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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e06b396191a29bcc371e67413956ad9f0ebb5ea518ae248d25dc905b9ab35cd' 
  AND token = 'bcCDFTrxDDs487ZFFB4PB3xExIEJ7u3bi42ZpSum61Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}