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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42abd37d25600f48caf83750d2f774144c9922bf2c52d9e0514d49698fc3ba00' 
  AND token = 'Yxazr0bC61PEvf6SMhTis+Agp+IyYex+bl0S40FCjBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}