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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c880f059e67ffd5f9d079b5665489d980dfc8600505f4e1b0e80d12e9f4bde6' 
  AND token = '2CnL8SF/8iS56z7VXGtnP7yB4adO7tTGIOKTLTlJejw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}