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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10be94ef6fd7ff4cb99b15dfcd9cf14dbf8eb9e0a9dea480055c1f4ca177e374' 
  AND token = '+0SjCxJqIKieE3SyqVG6PqOlN+XvQAg8Wnuv5UHanAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}