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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c561b9fda049811d488b84c552c6c6ecb3c87c8c3bc60c420eabe2d39c42187' 
  AND token = 'vXIMbZxOdr1HgwSW6cVHsd6hAvBd7zRu5iqtJJzBlGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}