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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88fdbad659f91292c3cfa329c7ac11a47c2f2c41c97df13f4337d7d81676bfdd' 
  AND token = 'UzJLndIQuA0SNu+k7qjVJVYyFVf+ThA2lvxHLO4WEW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}