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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e467e43536cd3f2db0b8a31761035b6bed0990c2134c536bef58f4781aa7fdf6' 
  AND token = 'I9ccs8qgrWAcpYecCihAd4oRtWgKEMbo4GTKmz0VT/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}