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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c99c94a9821d95f2de173035483e9264cc5cfa12d877490e9b348991dff9017a' 
  AND token = 'bRwBgMFGAnM6Vos1pJdKcoP9hwPm3liqHPeg/I9P5VE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}