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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '200866c7f63ba3d435fbd29f9b7d2e29d60fb61eaa01c91a0cf8acede8bcc250' 
  AND token = 'jz5OEDp6ZbqkOzwUB4TYfMAJsGuuen2vX4ny+W2wdpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}