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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0481043bc77762cbd4c7b172b0a40c7495c912a2845f5c39f683e1e1dccba5f9' 
  AND token = 'x0Vw65ftBxXj0HkBBHo3oWvI8J4ES9kfuv62KTZ2msM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}