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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66e1d3b52c48c58b2bea9d5124b3958d5c547ccfeed15d9d2d6e644d7fecc34a' 
  AND token = '8BiGVFw9dYuS4nH2Yc52WCjSPgv560g+2U9e4U6x8Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}