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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ef01acd67e2af3aff093b3c20e1165f4c814ac2c71616e20c09e339300c4db1' 
  AND token = '1ER9UiKTWUMQg1zyE2/e2vWgur9Tn7ATlkM+JipN0Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}