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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '975cb81115abd68bdd1a1d867b6033f83160c79e7efa9da32cd8f07b767973b7' 
  AND token = '9OWUevYLlQ/mJk4GHjP0D+OOmzfPdqHNa9MReLsRZ9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}