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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8fe3ebf2d5af7c7d8de883b624267a8e639575dac0688be4620a37c5505686c' 
  AND token = 'hlE/7QJpVyyff7495MWFJoPZjoytaQvOJbgBZ/0bg6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}