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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0e57ec7fad9aa14ee85d97fdac07c3597412be4ceea86548702e1a64abd08d8' 
  AND token = 'OHNEC6FMcq/RkYG4jMY+TYeSK7bBCu8C5btNAwY5mnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}