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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '488dc8241bf64f0febc491ecc353d2aea5284cf0f25bf8211fdeb9cc3de3054c' 
  AND token = '2bH3JPVgraw0EIhqGOLZCUu019Ahuo2fDfcxwTZIUHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}