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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8df51f9b01ae2a9f0c7daf0f1fe9025b33896d27c862da377fb4db0caca44be' 
  AND token = 'VrbUDQbkGYtckhBilY9jak72S7Ism6r+yOn07KHol2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}