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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b219baa6c06c820b1d2a2a70a7bd38830fe1b3e81aeb00149b55e33c27b34f' 
  AND token = 'nQpSXrzrsuU8m1kN69LcEexQKLo6oqKAzP8nQ9cYYP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}