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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '503e4b7624b91b9a9e7feb6b067cd4fa02f025314f4c8d2e6464121898bba8b1' 
  AND token = '0JK3Pi49EOmKx4e2EHFeDkz1kE0xN0EuDh+yWTDLxcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}