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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e037df7e4f20c340680a1aa095c0a0bc000dac0e905b6b93a9f11a4a24bdb3af' 
  AND token = 'VzxZQjmUQIkxM/EvcNJBj4A4dJWKaDc9XRTH4PgolVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}