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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc18c5fbbc69aa64af72d5d6679300814d04f37be862f1134d6228c8004025c8' 
  AND token = 'yc93v89ORdQy6zyywxiMxDzRBwMRKbCRLt60fmTqrVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}