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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb981a2792b9c325eac0fef3920954495316adcac347166a4e731b03ce8a8659' 
  AND token = '5H/XoYYWackxR7fuquRFgBMByDegWqznTDUxFeRpU/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}