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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2549dcf0c41bb59f14971144230fd2b166dd25e6cd94ecb96899ee6e4982524a' 
  AND token = 'A7zKnuDQIEah6m+hgJTmefZ+JEf20Zl2TA86ivQK89Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}