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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a511066aa477a8f253aa5920f523b44ade2a58079a80e4dabc2a5815929e7b15' 
  AND token = 'BqARfp7/4fMV9bgdtT2757rthotx4VkxB2vRyq9xyos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}