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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3565a89a6dcc5776b1e146d84fde2a9f7c4ec6cf42d738ab8131c82b8257c82c' 
  AND token = 'NafiQb4/tnZEbZXcbePcnrb3M0kxRQmzZPDv+6DQ00s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}