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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a08df8f83d56974e6a5ee988ef05061349a032eddd75c0a9587bfa988cabfb' 
  AND token = 'MZ6x+pUcotzCttje/MwQcElbA5bXNyBeY9tsEVSWlfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}