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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6dce643bce18593e2b074c195747adbdc841b8c7a737541b2b2a524f799fc94' 
  AND token = '202GPK8XKc1rtslDMwikU43Boa+50jRO2zYkMiwCb7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}