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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7912ea8c1e1db030ef0f65f2aa3cac1b97e01cbd46bc5879151fbcfa9296bfc2' 
  AND token = 'v/8jdn2qwSkUcEZ+lYf1uoSx5Q/THZWqP1CwvYjhLd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}