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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163e0bbd9b4000c11378b92d495f6044bc172e27a2651206a0c778052171ebac' 
  AND token = 'TDgsEyk3257MV4UUsFD4gHZNJATOvM6PVC60VTM0pIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}