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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fdbc4d05ceddcc2a7a6427cfb435022494b76f20880448ab976b6f1553a4a38' 
  AND token = 'EpOpS2oylV0Wcuc6u3royza+hv3X5RW0D2OYpb0ggns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}