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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eb80da4b0a2b668c5a9c5cf5b82d57715d730b9008ea1870910934c1b588891' 
  AND token = 'fDdsb1HQAIna4PrAtrbw2hZb1njP0S8bHLAyQAaq3qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}