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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308453f6c7d5d4a2223402d128ee26e5d33b8b9c8920a0b20e2980f2ce7494fd' 
  AND token = 'u93IYz28/MtWXaCMOYeyoTlcG1zT49NR2KwtxpSMm38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}